Providing solutions to complex formulation challenges
of new drugs are
Increasing solubility and bioavailability
Poor water solubility of active pharmaceutical ingredients (APIs) is a major cause of attrition in the pharmaceutical industry. We help drugs reach their full therapeutic potential by enhancing bioavailability. Nanoforming increases the specific surface area of API particles, enabling significant improvements in dissolution rate and thus bioavailability. The creation of a robust method for producing uniform and stable nanoparticles has initiated a new era of novel drug delivery applications that will transform the healthcare sector.
We help partners around the
world by nanoforming APIs for
a range of therapeutic areas
The benefits of our best-in-class nanoforming services
See what small can do for you
Our process is designed to rapidly define the best route for enhanced particle engineering that fits the individual requirements of our partners.
We first perform an initial evaluation to understand compound characteristics. Our extensive conversations with partners enable us to fully define what we aim to achieve and the challenges involved.
Proof of concept
A proof of concept study is initiated to determine the feasibility of nanoforming the material. A proof of process study is then performed to find the optimal process parameters for consistent, reproducible results.
Scalability assessment and
A demonstration batch is produced at a larger scale before being moved into our GMP facilities for clinical production.